Program for predicting multiple genes in genomic DNA sequences using HMM gene model plus similarity with known mRNA/EST.
The program can be used if you know mRNA/EST sequence that is homologous to that of predicted gene. First, run any ab initio gene finding program such as Fgenes or Fgenesh. Then, run BLAST DB search with each predicted exon. If homologous mRNA is found, use it to improve accuracy of assembly of your predicted gene.